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CHAMPIX is indicated for smoking cessation in adults.

Treatment with CHAMPIX for 12 weeks helps make quit success achievable.1

Dosing information for CHAMPIX is summarised in the table below. Please refer to the CHAMPIX Summary of Product Characteristics for further information on recommended dosing and for information on the safety and tolerability of CHAMPIX.

CHAMPIX dosing recommendations

  Dosing1 The Patient

Week 1

CHAMPIX titration

Days 1–3: 0.5 mg od

Days 4–7: 0.5 mg bd

Sets a quit date (ideally during Week 2) before starting CHAMPIX  treatment1

Continues to smoke


Week 2

Begin 1 mg bd

Quitting period

Quits during Week 2


Patients unable or unwilling to set a quit date during Week 2 can choose a quit date during Weeks 2–5.1

Weeks 3–12

Continue on 1 mg bd

12 weeks of CHAMPIX treatment will support your patients' quit attempts1

Weeks 13–24

Consider an additional 12 weeks of CHAMPIX treatment Double the odds of your successful patients staying quit at 24 weeks by prescribing an additional 12 weeks of CHAMPIX2**

**An additional 12-week course of CHAMPIX or placebo was given to those patients who successfully quit smoking with the original 12 weeks of CHAMPIX treatment. (OR=2.48, 95% CI: 1.95–3.16, p<0.001)

Initiating treatment with CHAMPIX

CHAMPIX can be prescribed as three 4-week packs: 

  • One 4-week starter blister pack 
  • Two 4- week follow on blister packs 


1. CHAMPIX Summary of Product Characteristics
2. Tonstad S et al. Effect of maintenance therapy with vareniciline on smoking cessation. A randomized controlled trial. JAMA 2006; 296:64-71.

PP-CHM-GBR-1776. April 2018

CHAMPIX dosage